Resist Temptation to Recommend OTC Dextromethorphan or Guaifenesin for Cough

What really works to treat coughs due to respiratory infections?

Patients often reach for OTC products with dextromethorphan and/or guaifenesin. But there's not much evidence they work.

Instead, advise adults to try an oral decongestant and FIRST-generation antihistamine (brompheniramine, etc). These help reduce the postnasal drip that can trigger coughs.

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