possible birth defects with long-term, high-dose fluconazole (Diflucan, etc)
September 2011
You'll hear new warnings about possible birth defects with long-term, high-dose fluconazole (Diflucan, etc).
But don't panic...this doesn't apply to the use of a single 150 mg dose of fluconazole for vaginal yeast infections.
The increased risk is seen in women taking 400 to 800 mg/day of fluconazole long-term during the first trimester for meningitis and other serious infections.
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