New Drugs

Brand/Generic Company Description
Ajovy
fremanezumab
Teva

An injectable anti-calcitonin gene-related peptide for migraine prevention in adults.

Anthim
obiltoxaximab
Elusys (U.S.)

An injectable monoclonal antibody for treatment and postexposure prophylaxis of inhalational anthrax.

Avsola
infliximab
Amgen

Biosimilar to Remicade.

Beovu
brolucizumab
Novartis

Intravitreal VEGF inhibitor for neovascular (wet) age-related macular degeneration.

Cabenuva
cabotegravir/rilpivirine
ViiV Healthcare

Extended-release injectable formulation for HIV-1 infection.

Cablivi
caplacizumab
Sanofi Genzyme

An injectable antithrombotic for acquired thrombotic thrombocytopenic purpura.

Darzalex SC
daratumumab
Janssen

New subcutaneous formulation for multiple myeloma.

Daurismo
glasdegib
Pfizer

An oral Hedgehog pathway inhibitor for newly-diagnosed acute myeloid leukemia.

Enspryng
satralizumab
Hoffmann-La Roche

An injectable monoclonal antibody for neuromyelitis optica spectrum disorders.

Firdapse
amifampridine
Catalyst Pharma (U.S.)/Kye Pharm

An oral potassium channel blocker for Lambert-Eaton myasthenic syndrome.

Gleolan
aminolevulinic acid
Medexus

An oral imaging agent used in patients with glioma to help visualize malignant tissue during surgery.

Ibsrela
tenapanor
Knight Therapeutics

An oral sodium/hydrogen exchanger 3 (NHE3) inhibitor for IBS-C.

Inqovi
decitabine/cedazuridine
Otsuka

An oral hypomethylating agent for myelodysplastic syndromes.

Inrebic
fedratinib
Celgene

New oral kinase inhibitor for splenomegaly and/or disease-related symptoms in patients with myelofibrosis.

Itulatek
white birch allergen extract
Alk-Abello

SL allergy immunotherapy for moderate to severe seasonal allergic rhinitis induced by pollen from birch, alder, and/or hazel.

Kanjinti
trastuzumab
Amgen

Biosimilar to Herceptin.

Mayzent
siponimod
Novartis

An oral sphingosine 1-phosphate receptor modulator for multiple sclerosis.

Nivestym
filgrastim
Pfizer

A biosimilar to Neupogen.

Nubeqa
darolutamide
Bayer

An oral antiandrogen for non-metastatic castration resistant prostate cancer.

Odomzo
sonidegib
Sun Pharma

Oral hedgehog pathway inhibitor for basal cell carcinoma.

Osnuvo
teriparatide
Avir Pharma

A biosimilar to Forteo.

Piqray
alpelisib
Novartis

Oral kinase inhibitor for advanced/metastatic breast cancer.

Polivy
polatuzumab
Hoffmann-La Roche

A monoclonal antibody for relapsed/refractory diffuse large B-cell lymphoma.

Qinlock
ripretinib
Deciphera (US)

Oral kinase inhibitor for gastrointestinal stromal tumours.

Reblozyl
luspatercept
Celgene/BMS

A erythroid maturation agent for red blood cell transfusion-dependent anemia in adults with beta-thalassemia.

Riximyo
rituximab
Sandoz

A biosimilar to Rituxan.

Rozlytrek
entrectinib
Hoffmann-La Roche

A tyrosine kinase inhibitor for advanced extracranial solid tumours, including brain metastases.

Ruxience
rituximab
Pfizer

A biosimilar to Rituxan.

Ruzurgi
amifampridine
Medunik Canada

An oral potassium channel blocker for Lambert-Eaton myasthenic syndrome.

Sarclisa
isatuximab
Sanofi-Aventis

A monoclonal antibody for refractory multiple myeloma.

Spravato
esketamine
Janssen

An intranasal NMDA antagonist for depression.

Tomvi
etomidate
Sterimax

A new injectable general anesthetic.

Tukysa
tucatinib
Seattle Genetics

An oral kinase inhibitor for advanced HER2-positive breast cancer.

Veklury
remdesivir
Gilead Canada

An injectable nucleotide prodrug for adult/adolescent COVID-19 patients with pneumonia requiring supplemental oxygen.

Vocabria
cabotegravir
ViiV Healthcare

Oral formulation (used with oral rilpivirine) for short-term treatment of HIV-1 infection (used before starting Cabenuva to assess tolerability or as oral bridging therapy for missed Cabenuva injections).

Vyndaqel
tafamidis meglumine
Pfizer

An oral transthyretin stabilizer for cardiomyopathy due to transthyretin-mediated amyloidosis.

Xenleta
lefamulin
Sunovion

An injectable pleuromutilin antibiotic for community-acquired pneumonia.

Xofluza
baloxavir marboxil
Hoffmann-La Roche

An oral antiviral for treating influenza.

Zeposia
ozanimod
Celgene/BMS

An oral sphingosine 1-phosphate receptor modulator for relapsing remitting MS.

Ziextenzo
pegfilgrastim
Sandoz

A biosimilar to Neulasta.

Brand/Generic Company Description
Atectura Breezhaler
indacaterol/mometasone
Novartis

A combination inhaled LABA/corticosteroid for maintenance treatment of asthma.

Bijuva
estradiol/progesterone
Knight Therapeutics

New capsule formulation for vasomotor symptoms associated with menopause.

Duobrii
halobetasol/tazarotene
Bausch Health

New formulation corticosteroid/retinoid lotion for plaque psoriasis.

Enerzair Breezhaler
indacaterol/glycopyrronium/mometasone
Novartis

New combination long-acting bronchodilator/steroid inhaler for asthma maintenance therapy.

Imvexxy
estradiol
Knight Therapeutics

Vaginal estrogen formulation for moderate to severe postmenopausal dyspareunia.

Kynmobi
apomorphine
Sunovion

Sublingual dopamine agonist for acute intermittent off episodes in Parkinson’s disease.

Nexplanon
etonogestrel
Merck

New subdermal implant formulation for contraception.

Peyona
caffeine citrate
Chiesi (Spain)

CNS stimulant for primary apnea in premature newborns.

Suboxone
buprenorphine/ naloxone
Indivior

New sublingual/buccal soluble film for opioid drug dependence.

Suvexx
sumatriptan/naproxen
Nuvo Pharm.

New oral triptan/NSAID combination for acute migraine.

Uceris
budesonide
Bausch Health

New rectal foam formulation for mild to moderate ulcerative colitis.

Brand/Generic Company Description
Fibristal
ulipristal
Allergan/AbbVie

Voluntary withdrawal from market by manufacturer due to risk of serious liver injury.