New Drugs

Brand/Generic Company Description
Calquence
acalabrutinib
AstraZeneca

An oral tyrosine kinase inhibitor for mantle cell lymphoma.

Demylocan
decitabine
Pendopharm

IV pyrimidine analogue for treatment of myelodysplastic syndromes.

Emgality
galcanezumab
Lilly

A calcitonin-gene related peptide receptor antagonist to prevent migraine.

Esperoct
turoctocog alfa pegol
Novo Nordisk

A recombinant PEGylated antihemophilic Factor VIII for prophylaxis and treatment in patients with hemophilia A.

Evenity
romosozumab
Amgen

A sclerostin inhibitor for treatment of postmenopausal osteoporosis in women at high risk for fracture.

Idhifa
enasidenib
Celgene

An agent for relapsed/refractory acute myeloid leukemia with IDH2 mutation.

Influvac Tetra
influenza vaccine
BGP Pharma/Mylan

New quadrivalent formulation flu vaccine for adults.

Lokelma
sodium zirconium cyclosilicate
AstraZeneca

A potassium binder for hyperkalemia.

Lorbrena
lorlatinib
Pfizer

An oral kinase inhibitor for ALK-positive metastatic non-small cell lung cancer.

Lutathera
lutetium (177Lu) oxodotreotide
Advanced Accelerator Apps.

IV radiopharmaceutical for gastroenteropancreatic neuroendocrine tumors.

Nerlynx
neratinib
Puma (U.S.)/Knight Therapeutics

An oral protein kinase inhibitor for early stage breast cancer.

Ogivri
trastuzumab
BGP Pharma/Mylan

First biosimilar to Herceptin.

Onpattro
patisiran
Alnylam Netherlands

An injectable agent for polyneuropathy of hereditary transthyretin-mediated amyloidosis.

Onstryv
safinamide
Valeo

An MAO-B inhibitor add-on therapy for "off" Parkinson's episodes in patients on stable doses of levodopa.

Oxervate
cenegermin
Dompé (Italy)

An ophthalmic recombinant human nerve growth factor for moderate or severe neurotrophic keratitis.

Skyrizi
risankizumab
AbbVie

A monoclonal antibody for moderate to severe plaque psoriasis.

Tibella
tibolone
BioSyent

Oral synthetic steroid hormone prodrug for vasomotor symptoms in postmenopausal women.

Trazimera
trastizumab
Pfizer

New biosimilar to Herceptin.

Truxima
rituximab
Celltrion/Teva

A monoclonal antibody for treating non-Hodgkin's lymphoma, chronic lymphocytic leukemia, and rheumatoid arthritis.

Ultomiris
ravulizumab
Alexion

A monoclonal antibody for paroxysmal nocturnal hemoglobinuria.

Verzenio
abemaciclib
Lilly

Oral protein kinase inhibitor for advanced or metastatic breast cancer.

Vitrakvi
larotrectinib
Bayer

An oral kinase inhibitor for treating solid tumours.

Vizimpro
dacomitinib
Pfizer

Oral pan-human epidermal growth factor receptor inhibitor for advanced/metastatic non-small cell lung cancer.

Vonvendi
von Willebrand factor, recombinant (vonicog alfa)
Shire

IV rVWF for treatment/control of bleeding episodes in von Willebrand disease.

Yescarta
axicabtagene ciloleucel
Gilead Sciences

A CD19-directed genetically modified autologous T cell immunotherapy for relapsed/refractory large B cell lymphoma.

Zejula
niraparib
GSK

A PARP enzyme inhibitor for recurrent ovarian cancer.

Zirabev
bevacizumab
Pfizer

A biosimilar to Avastin.

Brand/Generic Company Description
Baqsimi
glucagon
Lilly

New intranasal formulation for severe hypoglycemia.

Combogesic
acetaminophen/ibuprofen
Aft Pharma.

A fixed-dose combination formulation for acute pain or fever reduction in adults.

Cystadrops
cysteamine HCl
Recordati Rare Diseases Canada

An ophthalmic cystine-depleting agent for corneal cystine crystal deposits in patients with cystinosis.

Dovato
lamivudine/dolutegravir
ViiV Healthcare

A new combination formulation for HIV-1 infection.

Envarsus PA
tacrolimus
Endo/Paladin Labs

A prolonged-release tablet formulation for prophylaxis of kidney or liver transplant rejection.

Ivozfo
fosfomycin
Verity Pharm.

New IV formulation antibiotic for infections in adults, children, and neonates.

Renvela
sevelamer
Sanofi-Aventis

New oral suspension formulation for hyperphosphatemia in children.

Tolak
fluorouracil
Hill Dermaceuticals

New 4% topical cream formulation for actinic keratosis lesions of the face, ears, and scalp.

Tremfya One-Press
guselkumab
Janssen

New single-dose auto-injector product.

Brand/Generic Company Description