Watch for TMP/SMX Rxs for Patients on Potassium-Boosting Meds

You'll hear more about possible harm when TMP/SMX is combined with meds that increase potassium (ACEIs, spironolactone, etc).

This interaction is more significant than previously thought...and is popping up on more drug interaction checkers.

Trimethoprim decreases urinary excretion of potassium.

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