Stay Alert for Skin Reactions With Allopurinol in Patients With CV Disease

A new study will raise concerns about a possible increased risk of severe skin reactions with allopurinol in patients with CV disease.

We know that allopurinol is associated with rare cases of severe skin reactions, such as Stevens-Johnson syndrome.

Now new data suggest the risk may be higher in patients with CV disease...especially with risk factors, such as chronic kidney disease or initial allopurinol doses over 100 mg/day.

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