Warning NOT to combine clarithromycin (Biaxin) with cisapride (Prepulsid) or pimozide (Orap)
March 1997
Abbott is now warning NOT to combine clarithromycin (Biaxin) with cisapride (Prepulsid) or pimozide (Orap).
This is similar to the current warning about taking clarithromycin with terfenadine (Seldane) or astemizole (Hismanal).
Clarithromycin slows the metabolism of these drugs in the liver. High levels of these drugs can cause fatal arrhythmias.
Get concise advice on drug therapy, plus unlimited access to CE
Pharmacist's Letter Canada includes:
- 12 issues every year, with brief articles about new meds and hot topics
- 200+ CE courses, including the popular CE-in-the-Letter
- Quick reference drug comparison charts
- Access to the entire archive