more reasons to advocate for judicious use of PPIs

See updated FDA information concerning the association of C. difficile and PPIs

You'll see more reasons to advocate for judicious use of PPIs.

PPIs (omeprazole, etc) are already associated with a higher risk of pneumonia...Clostridium difficile diarrhea...and fractures. They might also decrease the ability of bisphosphonates to prevent fractures.

Now you'll see a warning that long-term use of PPIs may cause hypomagnesemia...possibly by decreasing magnesium absorption.

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