New precautions about not taking Allegra with orange juice are raising questions about a new kind of fruit juice interaction

June 2011

New precautions about not taking Allegra with orange juice are raising questions about a new kind of fruit juice interaction.

Orange, grapefruit, and apple juice can DECREASE absorption of fexofenadine (Allegra) and other drugs in the gut.

Drinking 300 mL of orange or grapefruit juice with fexofenadine can reduce blood levels by about 40%...and MIGHT make it less effective.

Get concise advice on drug therapy, plus unlimited access to CE

Pharmacist's Letter Canada includes:

12 issues every year, with brief articles about new meds and hot topics
200+ CE courses, including the popular CE-in-the-Letter
Quick reference drug comparison charts
Access to the entire archive

Subscribe Today!

Already a subscriber? Log in

Volume pricing available. Get quote

Table of Contents

Cardiology HIGHER blood pressure goals in some elderly patients
Drug Interactions New precautions about not taking Allegra with orange juice are raising questions about a new kind of fruit juice interaction
Psychiatry more emphasis on the treatment of bipolar disorder
Dermatology the differences between all the imiquimod creams now that Vyloma is approved in Canada
Dermatology new combo acne treatment with Tactuo
Diabetes pregabalin (Lyrica) is "preferred" for treating painful neuropathy in diabetes patients
Needles & Syringes selecting the correct needle length and gauge for intramuscular and subcutaneous injections
Respiratory & Allergy patients with cystic fibrosis will have an alternative to nebulized tobramycin with the new Tobi Podhaler
Vaccines Gardasil is now approved in Canada for women up to age 45
Pediatrics whether PPIs (omeprazole, etc) are useful for treating gastroesophageal reflux in infants
Women's Health Is it okay for women to use OTC emergency contraceptives (Plan B, etc) repeatedly as their primary contraceptive
Dyslipidemia more focus on diet and exercise for high triglycerides