Resist Temptation to Recommend OTC Dextromethorphan or Guaifenesin for Cough
What really works to treat coughs due to respiratory infections?
Patients often reach for OTC products with dextromethorphan and/or guaifenesin. But there's not much evidence they work.
Instead, advise adults to try an oral decongestant and FIRST-generation antihistamine (brompheniramine, etc). These help reduce the postnasal drip that can trigger coughs.