New concerns are emerging about respiratory depression in kids taking tramadol

November 2015

New concerns are emerging about respiratory depression in kids taking tramadol...especially after tonsillectomy or adenoidectomy.

Using tramadol off-label in kids has become more popular...since acetaminophen with codeine has fallen out of favour due to toxicity risk.

Patients who are ultrarapid CYP2D6 metabolizers convert too much codeine to morphine and may develop toxic blood levels. On the other hand, poor 2D6 metabolizers may not get adequate pain relief.

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Pediatrics New concerns are emerging about respiratory depression in kids taking tramadol

New concerns are emerging about respiratory depression in kids taking tramadol

Get concise advice on drug therapy, plus unlimited access to CE

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