Be Aware of Possible Liver Failure with Holkira Pak or Technivie

February 2016

Warnings that Holkira Pak or Technivie can cause liver failure may have hepatitis C patients asking you if they should stop their meds.

Health Canada warnings are based on cases of liver decompensation and failure...in some cases leading to transplant or death.

Holkira and Technivie combine ombitasvir, paritaprevir, and low-dose ritonavir. Holkira also contains dasabuvir.

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Table of Contents

Antithrombotics Don't Delay Restarting Anticoagulation in Atrial Fib Patients After GI Bleeding
Heart Failure Prevent Med-Related Problems to Reduce Heart Failure Readmissions
Diabetes Caution about ketoacidosis, UTIs, and other serious ADRs with the SGLT-2s
Diabetes Suggest New Glucose Meter Technology For the Tech Savvy
Neurology & Pain Don't Jump to Buprenorphine Before Non-Opioids for Chronic Pain
Fall Risk Caution About Falls with SELECTIVE Alpha-blockers
Vaccines Give injections in the right spot to avoid shoulder injuries
Cough & Cold Avoid ORAL Phenylephrine
Hepatitis C Be Aware of Possible Liver Failure with Holkira Pak or Technivie
Acne Reassess Acne Treatments After 2 or 3 Months
Women's Health Don't Shun All SSRIs During Pregnancy
Hyperkalemia Suggest Low-Cost Treatments for High Potassium