Avoid Even One Dose of Fluconazole in Pregnant Women

New warnings will raise concerns about a possible increased risk of miscarriage with a single dose of fluconazole (Diflucan One, etc).

Vaginal azoles (miconazole, etc) are first-line for vaginal candidiasis in pregnancy. But the hassle of using a vaginal product for a week may lead to women wanting to use oral fluconazole instead.

Current labelling warns about birth defects with LONG-term use of HIGH-dose fluconazole... 400 to 800 mg/day.

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