Put Torsades Risk With Cholinesterase Inhibitors in Perspective

You’ll hear about an increased risk of QT prolongation and torsades with cholinesterase inhibitors (donepezil, etc).

These meds are commonly prescribed for Alzheimer’s or Parkinson’s dementia. About 3 million Rxs are dispensed in Canada each year.

Cholinesterase inhibitors already have warnings about bradycardia. But now Health Canada is expanding the warnings to include the risk of QT prolongation and torsades.

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