more emphasis on avoiding valproate during pregnancy

January 2010

See the March 2011 FDA alert concerning the increased risk of cleft lip/palate with use of topiramate during pregnancy.

You'll see more emphasis on avoiding valproate during pregnancy.

We've known about this problem for years...but not enough women are getting the message.

And valproate (Depakene, Epival, etc) is being used more in young women for mood disorders and migraines...in addition to seizures.

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Table of Contents

Cardiology The Ezetrol controversy and New Year's resolutions will spark new emphasis on treating lipids
Psychiatry increasing use of atypical antipsychotics in children
Respiratory & Allergy whether saline nasal irrigation or "neti pots" INCREASE the number of sinus infections
Women's Health oral bisphosphonates (Fosamax, etc) might decrease the risk of breast cancer
Women's Health more emphasis on avoiding valproate during pregnancy
Supplements high-dose folic acid supplements might INCREASE cancer risk
Supplements ensuring kids get enough vitamin D
Gastroenterology Ondansetron is being used more for acute nausea and vomiting
Anticoagulants whether dosage changes are needed for the new, LOWER potency unfractionated heparins
Anticoagulants whether warfarin is beneficial for MODERATE-risk patients with atrial fibrillation
Obesity & Weight Loss some people will be trying unusual products for weight loss
Interactions a specific list of drugs to avoid with Plavix