misconceptions about grapefruit juice interactions
February 2007
There are still misconceptions about grapefruit juice interactions.
We've known for years that grapefruit inhibits CYP3A4 and P-glycoprotein in the gut...and that this increases levels of some calcium channel blockers (felodipine, etc), statins (lovastatin, simvastatin), antiarrhythmics (amiodarone), and others.
But misunderstandings still cloud the best way to handle this.
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