stronger warnings about quetiapine (Seroquel, etc) and QT prolongation

September 2011

You'll see stronger warnings about quetiapine (Seroquel, etc) and QT prolongation.

Many of the antipsychotics can prolong the QT interval...but not all of them are associated with torsades or sudden death.

Torsades with quetiapine is very rare...and usually linked to an overdose. But the problem is that you can't predict who will get it.

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Table of Contents

Cardiology the risk of stopping aspirin, clopidogrel, or other antiplatelet drugs too soon
Hepatitis C two new protease inhibitors for chronic hepatitis C, Incivek (telaprevir) and Victrelis (boceprevir)
Statins the interaction between simvastatin (Zocor, etc) and amlodipine (Norvasc, Twynsta, etc)
Migraine Axert (almotriptan) is now the first triptan approved for treating migraines in adolescents
Gastroenterology stronger warnings from Health Canada about movement disorders with metoclopramide
Acetaminophen new lower dosing on Tylenol (acetaminophen) products
Infectious Diseases the emergence of a new strain of ceftriaxone-resistant gonorrhea
Geriatrics "START" and "STOPP" instead of the Beers criteria to evaluate appropriate med use in the elderly
Psychiatry stronger warnings about quetiapine (Seroquel, etc) and QT prolongation
Anticoagulants how to reverse bleeding due to Pradax or Xarelto
Parkinson's Disease treating Parkinson's disease AFTER the "honeymoon" is over
Oral Health new topical cold sore ointment called ColdSore-FX