Does it ever make sense to dose extended-release metformin or basal insulin twice daily

November 2012

Does it ever make sense to dose extended-release metformin or basal insulin twice daily?

Yes, sometimes. Giving these diabetes meds twice a day instead of once can decrease adverse effects...or increase efficacy.

Extended-release metformin dosing can be split and given BID if once-daily dosing causes too much GI upset.

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Table of Contents

Diabetes whether EVERY patient with type 2 diabetes should take an ACE inhibitor or ARB, aspirin, and statin
Asthma inhaled corticosteroids PRN for some asthma patients
Asthma controversy about whether long-acting beta-agonists (salmeterol, etc) should be stopped once asthma is controlled
Women's Health alleviate concerns about using domperidone to increase breast milk production
Cardiology bigger push to limit NSAIDs in heart attack patients INDEFINITELY
Infectious Diseases Many patients with strep throat get an antibiotic dosed more frequently than necessary
Diabetes About 25% of your patients over age 65 have type 2 diabetes
Diabetes Does it ever make sense to dose extended-release metformin or basal insulin twice daily
Contraceptives counsel women about emergency contraception (EC)
Aspirin myths about aspirin
Thyroid Disorders the proper way to take levothyroxine