Does it ever make sense to COMBINE an ACEI with an ARB...or aliskiren (Rasilez) with an ACEI or ARB

Does it ever make sense to COMBINE an ACEI with an ARB...or aliskiren (Rasilez) with an ACEI or ARB?

Very rarely.

This became popular years ago...prescribers hoped that combining these renin-angiotensin system blockers would lead to better outcomes.

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