Advise Taking SGLT2 Inhibitors in the Morning...Due to Their Diuretic Effect

October 2015

Jardiance (jar-DEE-ans, empagliflozin) will be the third SGLT2 inhibitor...after Invokana (canagliflozin) and Forxiga (dapagliflozin).

These "flozins" inhibit sodium-glucose co-transporter 2 (SGLT2) in the kidney...leading to increased glucose excretion in the urine.

They lower A1C by about 0.7 to 1%...lower systolic blood pressure by 3 to 5 mmHg...reduce weight by 2 to 3 kg...and have a low risk of hypoglycemia when used alone.

Get concise advice on drug therapy, plus unlimited access to CE

Pharmacist's Letter Canada includes:

12 issues every year, with brief articles about new meds and hot topics
200+ CE courses, including the popular CE-in-the-Letter
Quick reference drug comparison charts
Access to the entire archive

Subscribe Today!

Already a subscriber? Log in

Volume pricing available. Get quote

Anticoagulants Use a Checklist to Help Patients Safely use DOACs
Women's Health Pick Your Go-To Oral Contraceptive to Simplify Choices
Cardiology Explain That Most "Statin-Intolerant" Patients Can Take One
Interactions Stop Repaglinide and Switch to Another Diabetes Med in Clopidogrel Patients
Oral Health Don't Recommend Antibiotics Before Dental Work for Prosthetic Joint Patients
Substance Use Disorder Be Alert to Unexpected Drugs of Abuse...Such as Bupropion
Diabetes Listen for Gliptin Patients Complaining of Severe Joint Pain
Sexual Dysfunction Be Aware of Addyi's (Flibanserin) Risks
HIV & AIDS Recommend Avoiding Some HIV Drugs With Simvastatin or Lovastatin
Respiratory & Allergy Be Aware Fluticasone FUROATE is AboutTwice as Potent as Fluticasone PROPIONATE
Testosterone Educate Men About Risks of Testosterone for "Low T"
Diabetes Advise Taking SGLT2 Inhibitors in the Morning...Due to Their Diuretic Effect

Advise Taking SGLT2 Inhibitors in the Morning...Due to Their Diuretic Effect

Get concise advice on drug therapy, plus unlimited access to CE

Table of Contents