Advise Taking SGLT2 Inhibitors in the Morning...Due to Their Diuretic Effect

Jardiance (jar-DEE-ans, empagliflozin) will be the third SGLT2 inhibitor...after Invokana (canagliflozin) and Forxiga (dapagliflozin).

These "flozins" inhibit sodium-glucose co-transporter 2 (SGLT2) in the kidney...leading to increased glucose excretion in the urine.

They lower A1C by about 0.7 to 1%...lower systolic blood pressure by 3 to 5 mmHg...reduce weight by 2 to 3 kg...and have a low risk of hypoglycemia when used alone.

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