Consider Zaxine After Usual Options for IBS With Diarrhea

The approval of Zaxine (ZAK-seen) for irritable bowel syndrome with diarrhea (IBS-D) in adults will lead to questions about IBS-D management.

Zaxine (rifaximin) is an oral antibiotic that has minimal systemic absorption...and may help by restoring the balance of bacteria in the gut.

But efficacy for IBS-D seems modest. Zaxine improves symptoms in about one in 10 patients...and over half of patients who respond will need another Zaxine course within 6 months.

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