a potential interaction between proton pump inhibitors and clopidogrel (Plavix)

April 2008

Clinicians are hearing about a potential interaction between proton pump inhibitors and clopidogrel (Plavix).

Patients commonly receive a PPI when getting clopidogrel...to decrease the risk of GI bleeding.

In vitro tests suggest that clopidogrel doesn't inhibit platelets as well in patients taking omeprazole.

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Table of Contents

Do statins cause cognitive impairment?
Cardiology growing evidence that calcium channel blockers may cause eczema and other skin problems
Cardiology Clopidogrel (Plavix) may compete with prasugrel (Effient)
Osteoporosis the importance of identifying patients at risk for a fracture due to osteoporosis
Respiratory & Allergy Patients are hearing that Spiriva (tiotropium) might increase the risk of stroke
Respiratory & Allergy Many patients have trouble using dry powder inhalers
Psychiatry whether antidepressants are effective
Dermatology how to relieve dry skin
Supplements health care professionals worried that natural health products will advertise false health claims
Supplements whether hawthorn is useful for heart failure
Interactions a potential interaction between proton pump inhibitors and clopidogrel (Plavix)
Pregnancy which antihypertensives are safe to use during pregnancy
Pediatrics some children getting high doses of amoxicillin
Storage & Disposal Reports of trace amounts of pharmaceuticals in water supplies are getting a lot of press
Health Canada will consider moving naproxen to OTC