more reports of rhabdomyolysis in patients taking both simvastatin and amiodarone (Cordarone, etc)

Authorities are getting more reports of rhabdomyolysis in patients taking both simvastatin and amiodarone (Cordarone, etc).

Package inserts already have information about muscle injury with this combo...but it keeps happening.

Amiodarone inhibits CYP3A4, which increases concentrations of simvastatin...lovastatin...and to a lesser extent, atorvastatin.

Get concise advice on drug therapy, plus unlimited access to CE

Pharmacist's Letter Canada includes:

  • 12 issues every year, with brief articles about new meds and hot topics
  • 300+ CE courses, including the popular CE-in-the-Letter
  • Quick reference drug comparison charts
  • Access to the entire archive

Already a subscriber? Log in

Volume pricing available. Get quote