Double-Check Dosing of Direct Oral Anticoagulants (DOACs) in Certain Patients

July 2017

How should you dose direct oral anticoagulants (DOACs) such as Pradaxa (dabigatran) in obese, low body weight, or dialysis patients?

There's not much evidence to guide DOAC dosing in these patients...so recommend sticking with warfarin when possible.

But follow these general guidelines if a DOAC is preferred.

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Table of Contents

Opioids Try Non-Opioid Options First for Chronic Noncancer Pain
Osteoporosis Sort Through Meds for Osteoporosis in Postmenopausal Women
Corticosteroids Know the Risks and Benefits of Short-Course Steroids
Heart Failure Don't Jump to Newer Drugs for Systolic Heart Failure
Antipsychotics Explain How Rexulti Compares to Other Atypical Antipsychotics
Transdermal Patches Help Avoid Common Errors With Transdermal Patches
UTIs Clarify How to Prevent Recurrent UTIs
Statins Re-Evaluate Statin Use in Older Patients WithOUT CV Disease
Anticoagulants Double-Check Dosing of Direct Oral Anticoagulants (DOACs) in Certain Patients
Musculoskeletal Explain Options for Treating Nighttime Leg Cramps
Diabetes Watch for Amputation Concerns With Diabetes Med Invokana
Med Adherence Take Steps to Reduce the Number of Return-to-Stock Rxs