Recommend Praxbind to Reverse Life-threatening Bleeding in Patients on Pradaxa

Praxbind (PRAKS-bynd, idarucizumab) will be the first agent in Canada to reverse the effects of the anticoagulant, Pradaxa (dabigatran).

We know that vitamin K reverses bleeding due to warfarin...but it doesn't work for Pradaxa and other direct oral anticoagulants (DOACs).

This means that managing bleeding with DOACs has been limited to stopping the drug, using blood products, supportive care, etc.

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